Darix Syrup: View Uses, Side Effects, Price and Substitutes | 1mg (2023)

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Manufacturer/ Marketer

Little Greave Pharmaceutical Pvt Ltd


Lactulose (3.35gm)


Store below 30°C

Product introduction

Darix Syrup is a type of sugar used to treat constipation. It is known as a laxative and makes your stool easier to pass by drawing water into your bowel. It is also used to treat hepatic encephalopathy (a liver disease causing confusion, tremor, decreased level of consciousness).

Darix Syrup can be taken with or without food. You should take this medicine as advised by your doctor. Use this medicine regularly to get the maximum benefit and try to take it at the same time(s) each day. Your dose may go up or down depending on how well it is working. Do not take more than you are advised to and, if you miss a dose, do not take an extra one to make up for it. This medicine takes at least 48 hours to work. Talk to your doctor if you are still constipated after 3 days.

The most common side effects are nausea and vomiting. These are usually mild and go away after a couple of days. Occasionally people develop serious side effects including severe diarrhea and electrolyte imbalance. Talk to your doctor straight away if you notice any of these.

Before taking this medicine, you should tell your doctor if you have diabetes or if you are unable to digest milk sugar (lactose intolerant). If you use this medicine over a long period of time, your doctor may want you to have occasional blood tests to check the mineral levels (e.g. potassium and sodium). Do not take other laxative medicines while taking this medicine and check with your doctor if you are pregnant or breastfeeding.

Uses of Darix Syrup

  • Treatment of Constipation
  • Treatment of Hepatic encephalopathy

Benefits of Darix Syrup

In Treatment of Constipation

Darix Syrup is a laxative that treats constipation by drawing water into the bowels thereby making stools softer and easier to pass. This medicine takes a couple of days to work (up to 3 days). Take it as instructed even it appears not to be working. Talk to your doctor if you are still constipated after 3 days. Constipation is a common problem that can cause significant pain and discomfort. This medicine can relieve discomfort and improve your quality of life. To prevent constipation from happening it may help to eat more high-fiber foods including fruit and vegetables and drink plenty of water.

In Treatment of Hepatic encephalopathy

Hepatic encephalopathy is a severe liver disease that can cause changes in brain function leading to confusion, tremors (shaking), sleep problems, and loss of consciousness. Darix Syrup is thought to work by lowering the level of a substance called ammonia in the blood which has harmful effects on the brain. If taken as prescribed, it can improve your brain function and reduce symptoms associated with hepatic encephalopathy.

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Side effects of Darix Syrup

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Darix

  • Abdominal pain
  • Nausea
  • Vomiting
  • Diarrhea

How to use Darix Syrup

Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Darix Syrup may be taken with or without food, but it is better to take it at a fixed time.

How Darix Syrup works

Darix Syrup works by drawing water into the intestine through osmosis, which makes the stool soft and easier to pass.

Safety advice



Consuming alcohol with Darix Syrup does not cause any harmful side effects.



Darix Syrup is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Breast feeding


Darix Syrup is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.



Darix Syrup does not usually affect your ability to drive.



Darix Syrup is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Darix Syrup may not be needed in these patients. Please consult your doctor.



Darix Syrup is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Darix Syrup may not be needed in these patients. Please consult your doctor.

What if you forget to take Darix Syrup?

If you miss a dose of Darix Syrup, skip it and continue with your normal schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Darix Syrup


Agilax Syrup

AGIO Pharmaceuticals Ltd


42% cheaper

Dufadin Syrup

Ethics Health Care Pvt Ltd


35% cheaper

Eziluk 3.35gm Syrup

Elisa Biotech Pvt Ltd


25% cheaper

Welluse 3.35gm Syrup

Medmom Pharmaceuticals LLP


12% cheaper

Enlooz 3.35gm Syrup

Rosswelt Biosciences


13% costlier

Quick tips

  • Darix Syrup is used in the treatment of constipation andhepatic encephalopathy.
  • Itshould preferably be taken at bedtimeas it requires 6 to 8 hours to show effect.
  • It is usually taken once a day as needed for up to 2 weeks. Take it exactly as prescribed by the doctor.
  • Takeitatleast 2 hoursafter taking other medicines, as it may interfere with the absorption of other medicines.
  • Inform your doctor if you have a history of stomach disorders such as appendicitis or a blockage in your bowel.
  • Some healthy tips to prevent constipation from happening:

    • Eat more fiber in your diet. Recommended daily intake is 20-35g
    • Drink 8-10 glasses of water per day
    • Exercise regularly at least 3 times per week
    • Do not hold in stool as that can worsen bowel issues

Fact Box

Chemical Class

Synthetic Disaccharide

Habit Forming


Therapeutic Class


Action Class

Osmotic laxatives/Purgative

Patient concerns

Darix Syrup: View Uses, Side Effects, Price and Substitutes | 1mg (1)

hepatic encephalopathy fro 12 October

Dr. Saurav Arora


Dear sir as your case is a chronic case it requires long case taking, examination and regular follow up, therefore, please visit a homeopath so that he can examine you and guide you accordingly.


Jaundice liver cirrhosis. Hepatic encephalopathy and ascites not edema with Sodium 107. Can we use tolvaptone?

Dr. Gurpreet Singh


Sir consult a hepatologist


Grade I hepatic fatty infiltration.

Shikha Mishra


Please consult doctor for this


Trigeminal neuralgia, frequent urine, loss of mental balance

Dr. Vikas Sharma


record suggests encephalopathy of unclear causeneeds to be investigated


Patient is having seizures with fever. Mri report shows metabolic encephalopathy.

Dr. Rahul Yadav


Hello, please consult a pediatric neurologist for detailed evaluation and management options.


What are the chances of getting hepatic cancer while suffering from chronic hepatitis?

Dr. Pushkar Mani


Which type of hepatitis


Suffering from anal itching # Pruritus ani

Dr. Ankur Kumar Tanwar


Is suffer from constipation


Darix Syrup: View Uses, Side Effects, Price and Substitutes | 1mg (2)


Q. How long does it take for Darix Syrup to work?

It takes about 2-3 days to see the benefits of the treatment. Talk to your doctor if you feel constipated even after 3 days of taking Darix Syrup.

Q. What is Darix Syrup used for?

Darix Syrup is used to treat constipation which is presented as infrequent bowel movements, hard and dry stools. It is also used in patients with hepatic encephalopathy which is a serious liver problem causing confusion, tremors and decreased level of consciousness.

Q. Is Darix Syrup a laxative?

Yes, Darix Syrup is a laxative which softens the stools by pulling in water from the body to the large intestine. It is also used to reduce the amount of ammonia in the blood of patients with liver disease.

Q. What are the side effects of taking Darix Syrup?

Darix Syrup very commonly causes diarrhea, flatulence, nausea, vomiting and abdominal pain. Diarrhea and abdominal pain occur due to a high dose. In such cases, the dose should be reduced. Flatulence may occur during the first few days of treatment and may disappear after sometime. This medicine may also cause electrolyte imbalance. However, this is an uncommon side effect.

Q. Is it okay to take Darix Syrup every day?

You should take Darix Syrup for as long as advised by your doctor. You may also take it for as long as constipation lasts, which may be up to a week. For hepatic encephalopathy, the treatment may be longer, even several months.

Q. Who should not be given Darix Syrup?

Darix Syrup should not be given to patients who are allergic to it or are intolerant to lactose (cannot process lactose). It should also be avoided in patients having galactosemia, a rare health problem where the body cannot process galactose.

Q. Can I take other laxatives along with Darix Syrup?

Usually, one laxative is sufficient to relieve constipation. In case you need more, your doctor may advise you to take one more laxative along with Darix Syrup. The risk of side effects is more with two laxatives.

Q. What if I take more than the recommended dose of Darix Syrup?

Taking more than the recommended dose of Darix Syrup may cause abdominal pain, electrolyte imbalance and diarrhea, which may last for a couple of days.

Q. How should Darix Syrup be taken?

You should take the prescribed amount in the measuring cup or spoon that is provided with the medicine. You can take it with water or fruit juice if you find it very sweet. Drink plenty of water for better results. Swallow it as soon as you keep it in mouth to prevent tooth decay which can occur if you take it for a longer time.

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Related lab tests

  • Ammonia
  • Liver Function Test
  • Potassium
  • Sodium
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    Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.


    1. Sharkey KA, Wallace JL. Treatment of Disorders of Bowel Motility and Water Flux; Anti-Emetics; Agents Used in Biliary and Pancreatic Disease. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1332.

    2. McQuaid KR. Drugs Used in the Treatment of Gastrointestinal Diseases. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 1079.

    3. Lactulose. Maidenhead, Berkshire: Intrapharm Laboratories Limited; 2015 [revised 12 Jan. 2017]. [Accessed 27 Mar. 2019] (online) Available from:Darix Syrup: View Uses, Side Effects, Price and Substitutes | 1mg (6)

    4. Drugs.com. Lactulose. [Accessed 27 Mar. 2019] (online) Available from:Darix Syrup: View Uses, Side Effects, Price and Substitutes | 1mg (7)

    5. Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:Darix Syrup: View Uses, Side Effects, Price and Substitutes | 1mg (8)

    Manufacturer/Marketer address

    406-The View Building,Opp. Tukoganj Police Station, Yashwant Niwas Road, Indore-452003 Madhya Pradesh

    Country of origin: India


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